Celastrol CAS 34157-83-0

CAS:34157-83-0

Tsarin Kwayoyin Halitta:C29H38O4

Nauyin kwayoyin halitta:450.61

EINECS:636-472-5

Ma'ana iri ɗaya:CELASTROL(SH); CELASTROL; Celastrol (Tripterin); CELASTROL(P)(DON ALLAH A KIRA); (20R)-3-Hydroxy-2-oxo-24-nor-D:A-fridoolean-1(10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1(10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

A bar saƙonka

Cikakken Bayani game da Samfurin

Saukewa

Alamun Samfura

Menene Celastrol CAS 34157-83-0?

Celastrol ba ya narkewa a cikin ruwa, yana narkewa a cikin dimethyl sulfoxide da anhydrous ethanol. An samo shi ne daga sinadaran da ke hana cutar kansa a cikin tsire-tsire kamar Thunder God Vine da South Snake Vine a cikin dangin Celastraceae. Wani ingantaccen mai hana proteasome, wanda aka tabbatar yana haifar da apoptosis na ƙwayoyin cutar kansa ta hanyar hana ayyukan proteasome.

Ƙayyadewa

Abu	Ƙayyadewa
Wurin tafasa	645.7±55.0 °C(An yi hasashen)
Yawan yawa	1.2
Wurin narkewa	219-230°C
pKa	4.78±0.70 (An yi hasashen)
λmax	424nm (MeOH) (haske)
Yanayin ajiya	-20°C

Aikace-aikace

Ana amfani da Celastrol don tantance abubuwan da ke ciki/ganowa/gwaje-gwajen magunguna, da sauransu. Tasirin magunguna: Yana da ƙarfi a cikin kaddarorin antioxidant, tasirin hana cutar kansa, da tasirin hana cutar rheumatoid. Ingantaccen maganin hana proteasome, wanda aka tabbatar yana haifar da apoptosis na ƙwayoyin cutar kansa ta hanyar hana ayyukan proteasome.