Celastrol CAS 34157-83-0

CAS:34157-83-0

Tsarin kwayoyin halitta:Saukewa: C29H38O4

Nauyin Kwayoyin Halitta:450.61

EINECS:636-472-5

Makamantuwa:CELASTROL (SH); CELASTROL; Celastrol (Tripterin); CLASTROL(P)(Don Allah KIRA); (20R) -3-Hydroxy-2-oxo-24-ba-D: A-friedolean-1 (10),3,5,7-tetren-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedela-1 (10),3,5,7-tetraene-29-oic acid; 2-Oxo-3-hydroxy-24-norfriedelane-1(10),3,5,7-tetraene-29-oic acidCelasterol

Bar Saƙonku

Cikakken Bayani

Zazzagewa

Tags samfurin

Menene Celasttrol CAS 34157-83-0?

Celastrol ba shi da narkewa a cikin ruwa, mai narkewa a cikin dimethyl sulfoxide da ethanol anhydrous. An samo shi daga kayan aikin rigakafin ciwon daji a cikin tsire-tsire irin su Thunder God Vine da Kudancin Snake Vine a cikin dangin Celastraceae. Ingantacciyar mai hana proteasome, wanda aka tabbatar don haifar da apoptosis cell ciwon daji ta hana ayyukan proteasome.

Ƙayyadaddun bayanai

Abu	Ƙayyadaddun bayanai
Wurin tafasa	645.7± 55.0 °C (An annabta)
Yawan yawa	1.2
Wurin narkewa	219-230 ° C
pKa	4.78± 0.70 (An annabta)
max	424nm (MeOH) (lit.)
Yanayin ajiya	-20°C

Aikace-aikace

Ana amfani da Celastrol don ƙaddara abun ciki / ganewa / gwaje-gwajen magunguna, da dai sauransu. Sakamakon Pharmacological: Yana da kaddarorin antioxidant masu ƙarfi, tasirin anti-cancer angiogenesis, da tasirin rheumatoid. Ingantacciyar mai hana proteasome, wanda aka tabbatar don haifar da apoptosis cell ciwon daji ta hana ayyukan proteasome.