Gishirin disodium na ATP CAS 987-65-5
Gishirin disodium na ATP wani sinadari ne na adenosine, wani nau'in nucleoside triphosphate mai aiki da yawa wanda ake amfani da shi azaman coenzyme don canja wurin kuzarin ƙwayoyin halitta a cikin ƙwayoyin halitta. Yana jigilar makamashin sinadarai a cikin ƙwayoyin halitta don metabolism. Ana amfani da gishirin disodium na ATP don haɗa analogues na deoxyadenosine diphosphate da aka gyara a matsayin ligands na masu karɓar P2Y1.
| Bayyanar | Foda fari ko foda mai launin fari ko foda mai lu'ulu'u, mai hygroscopic. |
| Girman ƙwayoyin cuta | −95% na ratsawa ta raga 80. |
| pH | 2.5~3.5 |
| Narkewa | Mai narkewa a cikin ruwa; ba ya narkewa a cikin ethanol da ether. |
| Oder | Ba tare da Oder ba |
| Yawan ruwa | 6.0%~12.0% |
| Chloride | ≤0.05% |
| Gishirin ƙarfe | ≤0.001% |
| Karfe masu nauyi | ≤0.001% |
| Jagora | ≤2.0ppm |
| Arsenic | ≤1.0ppm |
1. Amfani da binciken masana'antu da kimiyya
(1) Kayan kwalliya na kayan kwalliya: an ƙara shi a cikin samfuran kula da fata masu hana tsufa, yana iya inganta laushin fata da sheƙi ta hanyar kunna metabolism na makamashin tantanin halitta.
(2) Ƙarin abinci: ana amfani da shi azaman mai ƙara abinci mai gina jiki a cikin abubuwan sha na wasanni da abinci mai amfani don sake cika kuzari cikin sauri.
2. Wuraren magani na asibiti
(1) Cututtukan tsarin zuciya da jijiyoyin jini: ana amfani da su don gazawar zuciya, ciwon zuciya, bugun zuciya da bugun jini na kwakwalwa, da sauransu, ta hanyar inganta metabolism na makamashin zuciya da faɗaɗa jijiyoyin zuciya (ƙara yawan kwararar jini da kusan 30%), rage alamun ischemia na zuciya. Misali, a cikin marasa lafiya da ke fama da ciwon zuciya mai tsanani, ATP disodium na iya rage lokacin faɗuwar kashi na ST da rage ƙimar kololuwar enzyme spectrum na zuciya.
(2) Cututtukan tsarin jijiyoyi: magani mai taimako na ci gaba da zubar jini a kwakwalwa, lalacewar kwakwalwa da kuma ci gaba da toshewar tsoka, ta hanyar shiga shingen jini-kwakwalwa (zuwa gawarwaki kusan kashi 65%), inganta gyaran membrane na ƙwayoyin jijiyoyi da sake farfaɗo da tsarin jijiyoyi, da kuma inganta saurin isar da jijiyoyi.
(3) Cututtukan da ke cikin metabolism: A cikin maganin hepatitis da cirrhosis, ATP disodium na iya haɓaka aikin mitochondrial na hepatocytes, hanzarta gyaran hepatocyte, da rage matakan ALT da AST; yana kuma da tasiri mai kyau akan rikice-rikicen ciwon suga (kamar neuropathy na gefe).
3. Yankunan aikace-aikace masu tasowa
(1) Tsarin isar da magunguna da aka yi niyya: Ana iya amfani da ATP disodium a matsayin mai gyara jigilar magunguna, tare da liposomes ko nanoparticles, don cimma isar da magunguna da aka yi niyya ta hanyar endocytosis mai karɓar karɓa. Misali, a cikin maganin ƙari, nanomedicines da aka gyara ta ATP na iya inganta ingantaccen kashe ƙwayoyin cutar chemotherapy a kan ƙwayoyin cutar kansa.
(2) Al'adar ƙwayoyin halitta da magungunan halittu: A matsayin muhimmin sashi na hanyar al'adar ƙwayoyin halitta, ATP disodium na iya haɓaka girma da bayyanar furotin na ƙwayoyin CHO, ƙwayoyin HEK293, da sauransu, kuma ana amfani da shi sosai a cikin samar da ƙwayoyin rigakafi na monoclonal.
25kgs/ganga, tan 9/kwantenar 20'
25kgs/jaka, tan 20/kwantenar 20'
Gishirin disodium na ATP CAS 987-65-5
Gishirin disodium na ATP CAS 987-65-5
